Photochemical and Electrochemical Strategies for Hydrodefluorination of Fluorinated Organic Compounds

Hydrodefluorination (HDF) is a very important fundamental transformation for conversion of the C−F bond into the C−H bond in organic synthesis. In the past decade, much progress has been achieved with HDF through the utility of low-valent metals, transition-metal complexes and main-group Lewis acids. Recently, novel methods have been introduced for this purpose through photo- and electrochemical pathways, which are of great significance, due to their considerable environmental and economical advantages. This Review highlights the HDF of fluorinated organic compounds (FOCs) through photo- and electrochemical strategies, along with mechanistic insights.