| Institution: | 1. School of Chemistry, Cardiff University, Park Place, Main Building, Cardiff, CF10 3AT UK
Lanzhou Petrochemical University of Vocational Technology, Lanzhou, 730060 P. R. China;2. School of Chemistry, Cardiff University, Park Place, Main Building, Cardiff, CF10 3AT UK |
| Abstract: | Xanthene derivatives have broad applications in medicines, fluorescent probes, dyes, food additives, etc. Therefore, much attention was focused on developing the synthetic methods to prepare these compounds. Binaphthyl-based xanthene derivatives were prepared through the oxidation of BINOLs promoted by the hypervalent iodine reagent iodosylbenzene (PhIO). Nine-membered lactones were obtained through a similar oxidative reaction when iodoxybenzene (PhIO2) was used. Additionally, one-pot reactions of BINOLs, PhIO and nucleophiles such as alcohols and amines were also investigated to provide alkoxylated products and amides in good to excellent yields. |
