Covalent Organic Frameworks (COFs) for Cancer Therapeutics |
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| Authors: | Qun Guan Le-Le Zhou Wen-Yan Li Dr Yan-An Li Prof Yu-Bin Dong |
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| Institution: | 1. College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for, Chemical Imaging in Universities of Shandong, Key Laboratory of, Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan, 250014 P.R. China;2. College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for, Chemical Imaging in Universities of Shandong, Key Laboratory of, Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan, 250014 P.R. China
These authors equally contributed to this work. |
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| Abstract: | As newly emerged crystalline porous materials, covalent organic frameworks (COFs) possess fascinating structures and some specific features such as modularity, crystallinity, porosity, stability, versatility, and biocompatibility. Besides adsorption/separation, sensing, catalysis, and energy applications, COFs have recently shown a promise in biomedical applications. This contribution provides an overview of the recent developments of COF-based medicines in cancer therapeutics, including drug delivery, photodynamic therapy (PDT), photothermal therapy (PTT), and combined therapy. Furthermore, the major challenges and developing trends in this field are also discussed. These recent developments are summarized and discussed to help encourage further contributions in this emerging and promising field. |
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| Keywords: | cancer covalent organic frameworks drug delivery nanomaterials phototherapy |
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