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Click Modification of Diazido Acridine Intercalators: A Versatile Route towards Decorated DNA Nanostructures
Authors:Dr Shahrbanou Moradpour Hafshejani  Dr Scott M D Watson  Dr Eimer M Tuite  Dr Andrew R Pike
Institution:School of Chemistry, Bedson Building, Newcastle University, Newcastle upon Tyne, NE1 7RU (UK)
Abstract:Diazido derivatives of 3,6‐diamino acridine (proflavine) intercalate into DNA and undergo functionalization through click chemistry to form 1D nanostructures with redox active, conductive nanowire, and fluorescent properties. This two‐step approach, intercalation followed by click modification allows for the controlled decoration of DNA nanostructures.
Keywords:click chemistry  DNA  nanomaterials  scanning probe microscopy
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