Click Modification of Diazido Acridine Intercalators: A Versatile Route towards Decorated DNA Nanostructures |
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Authors: | Dr Shahrbanou Moradpour Hafshejani Dr Scott M D Watson Dr Eimer M Tuite Dr Andrew R Pike |
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Institution: | School of Chemistry, Bedson Building, Newcastle University, Newcastle upon Tyne, NE1 7RU (UK) |
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Abstract: | Diazido derivatives of 3,6‐diamino acridine (proflavine) intercalate into DNA and undergo functionalization through click chemistry to form 1D nanostructures with redox active, conductive nanowire, and fluorescent properties. This two‐step approach, intercalation followed by click modification allows for the controlled decoration of DNA nanostructures. |
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Keywords: | click chemistry DNA nanomaterials scanning probe microscopy |
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