Electrochemical Oxidative C−H/N−H Coupling between γ‐Lactams and Anilines |
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| Authors: | Ming Gong Prof Dr Jing‐Mei Huang |
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| Institution: | Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, Guangdong, P. R. China |
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| Abstract: | A mild method for the direct C?H/N?H coupling between γ‐lactams and anilines through electrochemical oxidation has been developed. The protocol proceeded smoothly without metal catalysts at room temperature to afford γ‐substituted γ‐lactams in good yields. It has been revealed that the quasi‐divided cell which provided high current density on the anode was crucial for this reaction. |
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| Keywords: | C− H/N− H coupling electrochemistry metal free γ -lactams anilines |
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