Preparation, characterization, and application of multistimuli-responsive microspheres with fluorescence-labeled magnetic cores and thermoresponsive shells |
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| Authors: | Deng Yonghui Wang Changchun Shen Xizhong Yang Wuli Jin Lan Gao Hong Fu Shoukuan |
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| Institution: | Department of Macromolecular Science, Fudan University, Shanghai 200433, China. |
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| Abstract: | Novel functional microspheres with multistimuli-responsive properties have been prepared and characterized. The as-prepared microspheres respond to an external magnetic field, environmental temperature, and ultraviolet radiation. The in vitro drug-loading efficiency and drug-release behavior of these microspheres demonstrated that they could be used as drug carriers for drug controlled release. The results of in vivo distribution investigations of these microspheres showed that they exhibit a high magnetic-targeting effect, which holds promise for applications in various fields such as magnetic drug targeting and tissue labeling, among others. |
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| Keywords: | core–shell structures drug carriers fluorescence magnetic properties thermoresponsive |
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