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Alkyne hydroamination triggered cyclizations: A powerful tool for the construction of biologically important structural motifs
Authors:Nitin T Patil  Vipender Singh
Institution:Organic Chemistry Division - II, Indian Institute of Chemical Technology, Hyderabad 500 607, Andhra Pradesh, India
Abstract:This review focuses mainly on recent endeavors in the field of cyclizations triggered by the catalytic hydroamination (formal or direct) of alkynes. The new strategies developed offer an efficient and convenient entry to several heterocycles of biological importance.
Keywords:Metal catalyst  Hydroamination  Cyclization  Cascade reactions  Biologically important scaffolds
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