| 锡类络合物在糖衍生物合成中的区域选择性 |
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| 引用本文： | 楼鑫,侯金松.锡类络合物在糖衍生物合成中的区域选择性[J].化学通报,2010,73(4). |
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| 作者姓名： | 楼鑫 侯金松 |
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| 作者单位： | 滁州学院化学与生命科学系;Food;Science;Environmental;Health;Dublin;Institute;Technology; |
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| 基金项目： | 安徽省应用化学省级重点学科建设项目(200802187C)资助 |
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| 摘 要： | 锡类化合物在选择性糖衍生物合成中应用得相当广泛,亚甲锡烷基方法在吡喃糖衍生物合成中体现了高区域选择性。本文从三丁基锡醚和二丁基锡缩醛与糖类形成的络合物结构出发,揭示了其区域选择性的根本原因在于通过聚合作用使得处于不同位置的羟基显示不同的电负性和亲核性;还讨论了吡喃糖类中不同类型的多元醇系统和锡络合后所表现的区域选择性。
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| 关 键 词： | 糖 二丁基氧化锡 三丁基锡醚 区域选择性 |
Regioselectivity of Tin-mediated Method in the Synthesis of Sugar Derivatives |
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| Seamas Cassidy,Lou Xin,Hou Jinsong,Seamas Cassidy.Regioselectivity of Tin-mediated Method in the Synthesis of Sugar Derivatives[J].Chemistry,2010,73(4). |
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| Authors: | Seamas Cassidy Lou Xin Hou Jinsong Seamas Cassidy |
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| Institution: | 1Chemcial & Biological Science Department;Chuzhou University;Anhui Chuzhou 239000;2 Food Science and Environmental Health;Dublin Institute of Technology;Ireland |
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| Abstract: | The stannylene based approach to regioselective sugar derivatization has been widely employed and reflects the satisfactory regioselectivity. The structure of dimer and polymer complex of tributyltin ether and dibutylstannylene acetal with sugar is well elucidated: the type of oxygen di-coordinated in an apical position of the dipyramid become more negative and hence more nucleophilic as the result of the electron-enriching effect of the tin atom redistribution, which account for the origin of regioselectiv... |
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| Keywords: | Carbohydrate Dibutyltin oxide Tributyltin ether Regioseletivity |
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