| 二氧噁唑酮参与的环化反应研究进展 |
| |
| 引用本文： | 黄昌凤,李文,刘环宇,刘想.二氧噁唑酮参与的环化反应研究进展[J].化学通报,2021,84(8):793-802. |
| |
| 作者姓名： | 黄昌凤 李文 刘环宇 刘想 |
| |
| 作者单位： | 广东药科大学医药化工学院 广东省化妆品工程技术研究中心 中山 528458,广东药科大学医药化工学院 广东省化妆品工程技术研究中心 中山 528458,广东药科大学医药化工学院 广东省化妆品工程技术研究中心 中山 528458,广东药科大学医药化工学院 广东省化妆品工程技术研究中心 中山 528458 |
| |
| 基金项目： | 国家自然科学基金项目(22001045)、广东省创新强校项目(2019KQNCX061)和省市共建重点学科建设专项资金资助 |
| |
| 摘 要： | 胺化反应在合成化学领域占据着重要地位。二氧噁唑酮是一种新型酰基乃春转移试剂,广泛应用于多种类型的胺化反应中。在温和条件下,过渡金属或非金属即可活化二氧噁唑酮,释放出二氧化碳并生成酰基乃春中间体,进而参与到胺化-环化反应中。该策略为构建噁唑、喹唑啉和喹诺酮等杂环化合物提供了新的思路。近年来,二氧噁唑酮参与的环化反应受到越来越多研究者的关注,并且取得了重要进展。本文从不同的催化体系着手就近年来二氧噁唑酮参与的环化反应进行概述。
|
| 关 键 词： | 二氧噁唑酮 金属催化 酸催化 环化反应 |
| 收稿时间： | 2020/12/26 0:00:00 |
| 修稿时间： | 2021/1/19 0:00:00 |
Research Progress of Dioxazolones in Cyclization |
| |
| Huang Changfeng,Li Wen,Liu Huanyu and Liu Xiang.Research Progress of Dioxazolones in Cyclization[J].Chemistry,2021,84(8):793-802. |
| |
| Authors: | Huang Changfeng Li Wen Liu Huanyu and Liu Xiang |
| |
| Institution: | School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering Technology Research Center,Guangdong Pharmaceutical University,School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering Technology Research Center,Guangdong Pharmaceutical University,School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering Technology Research Center,Guangdong Pharmaceutical University,School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering Technology Research Center,Guangdong Pharmaceutical University |
| |
| Abstract: | Amination plays an important role in the field of synthetic chemistry. Dioxazolones are a new acyl Nachun transfer reagent, which is widely used in many kinds of amination reactions. Under mild conditions, Dioxazolones can be activated by transition metals or nonmetals to release carbon dioxide and form acyl nitrene intermediates, which participate in amination cyclization reaction. This strategy provides a new way to construct heterocyclic compounds such as oxazole, quinazoline and quinolone. In recent years, more and more attention has been paid to the cyclization of dioxazolones, and important progress has been made. In this paper, the cyclization of dioxazolones in recent years was reviewed from different catalytic systems. |
| |
| Keywords: | dioxazolones metal catalysis acid catalysis cyclization reaction |
|
| 点击此处可从《化学通报》浏览原始摘要信息 |
| 点击此处可从《化学通报》下载免费的PDF全文 |
|
