| 3,3'-(苯亚甲基)双吲哚的制备―一个推荐的有机化学合成实验 |
| |
| 引用本文： | 陈正旺,刘良先.3,3''-(苯亚甲基)双吲哚的制备―一个推荐的有机化学合成实验[J].化学通报,2014,77(9):922-924. |
| |
| 作者姓名： | 陈正旺 刘良先 |
| |
| 作者单位： | 赣南师范学院化学化工学院 赣州341000 |
| |
| 基金项目： | 江西省高等学校教学改革研究省级课题 |
| |
| 摘 要： | 本文介绍了3,3’-(苯亚甲基)双吲哚的制备和柱层析分离实验的原理和操作步骤。该实验具有以下特点:(1)反应时间短,30min左右便可完成;(2)产物为粉红色,在进行硅胶板层析和层析柱时比较直观,适合于学生的实验教学;(3)反应物、催化剂和产物的极性相差很大,容易进行柱层析分离产物。该实验特别适合于综合性大学和地方高等师范院校化学和相关本科专业的"有机化学实验"或"综合化学实验"进行开设。
|
| 关 键 词： | 有机化学实验 有机合成 吲哚 Friedel-Crafts反应 |
| 收稿时间： | 1/1/2014 12:00:00 AM |
| 修稿时间： | 2014/1/25 0:00:00 |
Preparation of 3,3'-(phenylmethylene)bis(1H-indole)- A proposed organic synthesis experiment |
| |
| Chen Zhengwang and Liu Liangxian.Preparation of 3,3''-(phenylmethylene)bis(1H-indole)- A proposed organic synthesis experiment[J].Chemistry,2014,77(9):922-924. |
| |
| Authors: | Chen Zhengwang and Liu Liangxian |
| |
| Institution: | Department of Chemistry and Chemical Engineering,Gannan Teacher College,Ganzhou,341000,Department of Chemistry and Chemical Engineering,Gannan Teacher College,Ganzhou,341000 |
| |
| Abstract: | In this paper, the general procedure for the preparation of 3,3"-(phenylmethylene)bis(1H-indole) was reported. It has several advantages: (1) the reaction was performed at 25 oC for 0.5 h, (2) the purification for the preparation of of pink product by flash chromatography on silica gel was particularly suitable for experimental teaching, (3) the product is easily separated by column chromatography because the polar difference of reactants, catalyst and product is very big. This experiment is opened particularly suitable for the chemical and related undergraduate of comprehensive university and normal university in . |
| |
| Keywords: | Organic Chemical Experiment Organic Synthesis Indole Friedel-Crafts Reaction |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
| 点击此处可从《化学通报》浏览原始摘要信息 |
| 点击此处可从《化学通报》下载免费的PDF全文 |
|
