| 石英晶体微天平传感器及其在生物检测中应用的研究进展 |
| |
| 引用本文： | 姜鹏飞,杨鸿成,季晨阳,陈柱,聂立波.石英晶体微天平传感器及其在生物检测中应用的研究进展[J].化学通报,2018,81(2):129-129. |
| |
| 作者姓名： | 姜鹏飞 杨鸿成 季晨阳 陈柱 聂立波 |
| |
| 作者单位： | 湖南工业大学生命科学与化学学院 株洲 412007,湖南工业大学生命科学与化学学院 株洲 412007,湖南工业大学生命科学与化学学院 株洲 412007,湖南工业大学生命科学与化学学院 株洲 412007,湖南工业大学生命科学与化学学院 株洲 412007 |
| |
| 基金项目： | 湖南省自然科学基金项目(2016JJ3053)；湖南省大学生研究性学习和创新性实验计划项目(201711535035) |
| |
| 摘 要： | 石英晶体微天平(Quartz crystal microbalance,QCM)是一种具有灵敏度高、免标记、可实时在线检测等优点的重要分析工具。在生物检测领域,QCM与多种信号放大方法相结合,广泛应用于对生物分子的高灵敏检测。新型耗散型QCM(QCM-D)通过对薄膜厚度、粘弹性等的研究,主要用于考察生物分子的吸附分离、构型变化等微观过程。本文主要阐述了QCM及QCM-D生物传感器的构建及其在DNA、蛋白质、细胞和微生物检测中的研究进展。
|
| 关 键 词： | 石英晶体微天平，生物检测，生物传感器 |
| 收稿时间： | 2017/8/20 0:00:00 |
| 修稿时间： | 2017/9/17 0:00:00 |
Progress in Quartz Crystal Microbalance and Its Application in Biological Detection |
| |
| Jiang Pengfei,Yang Hongcheng,Ji Chenyang,Chen Zhu and Nie Libo.Progress in Quartz Crystal Microbalance and Its Application in Biological Detection[J].Chemistry,2018,81(2):129-129. |
| |
| Authors: | Jiang Pengfei Yang Hongcheng Ji Chenyang Chen Zhu and Nie Libo |
| |
| Institution: | College of Life Science and Chemistry,Hunan University of Technology,College of Life Science and Chemistry,Hunan University of Technology,College of Life Science and Chemistry,Hunan University of Technology,College of Life Science and Chemistry,Hunan University of Technology,College of Life Science and Chemistry,Hunan University of Technology |
| |
| Abstract: | Quartz crystal microbalance (QCM) is a significant analytical tool which has the advantages of high sensitivity, label-free and real-time detection. In the field of biological detection, QCM combining with signal amplification methods is wildly used in ultrasensitive detection of biomolecules. The novel QCM with dissipation (QCM-D) is mainly used to investigate the microscopic processes such as adsorption/desorption and configuration change of biomolecules by studying the thickness and viscoelasticity of the thin film. This paper reviewed the construction of QCM and QCM-D biosensors as well as their research progress in the detection of DNA, protein, cell and microorganism. |
| |
| Keywords: | Quartz crystal microbalance Biological detection Biosensor |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《化学通报》浏览原始摘要信息 |
| 点击此处可从《化学通报》下载免费的PDF全文 |
|
