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纳米颗粒复合材料增强的葡萄糖生物传感器
引用本文:孟宪伟,唐芳琼,冉均国,苟立.纳米颗粒复合材料增强的葡萄糖生物传感器[J].化学通报,2001,64(6):365-367,364.
作者姓名:孟宪伟  唐芳琼  冉均国  苟立
作者单位:[1]四川大学无机材料系,成都610065 [2]中国科学院感光化学研究所,北京100101
基金项目:国家自然科学基金!(6 9772 0 39),教育部博士点基金资助项目
摘    要:二氧化硅和金或铂组成的复合纳米颗粒可以大幅度地提高葡萄糖生物传感器的电流响应,其效果明显优于这三种纳米颗粒单独使用时对葡萄糖生物传感器的增强作用。除了具有吸附浓缩效应,吸附定向和量子尺寸颗粒 应外,复合纳米颗粒比单独一种纳米颗粒更易于形成连续势场,降低电子在电极和固定化酶间的迁移阻力,提高电子迁移率,有效地加速了酶的再生过程,因此复合纳米颗粒显著增强了传感器电流响应。

关 键 词:葡萄糖氧化酶  生物传感器      二氧化硅  固定化酶  纳米颗粒复合材料

Glucose Biosensor Enhanced by Nanoparticle Composite
Meng Xianwei,Tang Fangqiong,Ran Junguo,GOU Li.Glucose Biosensor Enhanced by Nanoparticle Composite[J].Chemistry,2001,64(6):365-367,364.
Authors:Meng Xianwei  Tang Fangqiong  Ran Junguo  GOU Li
Abstract:The nanoparticle composite of silica and gold or platinum can significantly enhance the current response of the glucose biosensor, which is more effective than one kind of the nanoparticles alone. Besides absorbed concentration effect, absorbed directional effect and quantum size effect, the nanoparticle composite was more liable to construct sequential field. It will decrease the resistance of electron transfer between the electrode and immobilized enzyme and increase the electron transfer rate, which could accelerate the regeneration of the enzyme. Thus the current response of biosensor by the nanoparticle composite was effectively increased.
Keywords:Nanoparticle    Composite  Glucose oxidase    Biosensor
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