| 1-甲基-2-咪唑醛缩甘氨酸Schiff碱配合物的合成与抑菌活性 |
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| 引用本文： | 吴爱芝,罗海燕.1-甲基-2-咪唑醛缩甘氨酸Schiff碱配合物的合成与抑菌活性[J].化学研究,2010,21(3):5-7. |
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| 作者姓名： | 吴爱芝 罗海燕 |
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| 作者单位： | 1. 广州中医药大学,中药学院,广东,广州,510006
2. 广州中医药大学,基础医学院,广东,广州,510006 |
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| 摘 要： | 以1-甲基-2-咪唑醛和甘氨酸缩合的Schiff碱为配体,合成了4种新的过渡金属配合物M(C7N3H8O2)(H2O)n]Cl O4(M=Co,Ni,Cu,Zn).经元素分析、摩尔电导率测定、红外光谱、电子光谱和热重分析确证配合物的组成和结构.初步抑菌活性实验表明,合成的配合物对多种菌株有明显的抑菌活性.
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| 关 键 词： | 1-甲基-2-咪唑醛 甘氨酸 Schiff碱配合物 合成 抑菌活性 |
Synthesis and Antimicrobial Activities of Complexes with Schiff Base Condensed by 1-Methyl-2-imidazolecarboxaldehyde and Glycine |
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| WU Ai-zhi,LUO Hai-yan.Synthesis and Antimicrobial Activities of Complexes with Schiff Base Condensed by 1-Methyl-2-imidazolecarboxaldehyde and Glycine[J].Chemical Research,2010,21(3):5-7. |
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| Authors: | WU Ai-zhi LUO Hai-yan |
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| Institution: | 1.School of Chinese Material Medica,Guangzhou University of Chinese Medicine,Guangzhou 510006,Guangdong,China;2.School of Basic Medicine,Guangzhou University of Chinese Medicine,Guangzhou 510006,Guangdong,China) |
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| Abstract: | Four new complexes with Schiff base condensed by 1-methyl-2-imidazolecarboxaldehyde and glycine were synthesized.The component and structures of these complexes were elucidated on the basis of element analysis,molar conductivity,IR spectra,electronic spectra and thermogravimetric analysis.The results showed these complexes displayed significant antimicrobial activities in primary treatment of three types of bacteria,S.aureus,B.subtilis and E.coli. |
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| Keywords: | 1-methyl-2-imidazolecarboxaldehyde glycine Schiff base complexes synthesis antimicrobial activities |
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