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七种天然黄酮类化合物对超氧阴离子自由基的清除活性
引用本文:李明静,庆伟霞,杨玉霞,赵东保,刘绣华,刘快之.七种天然黄酮类化合物对超氧阴离子自由基的清除活性[J].化学研究,2006,17(4):73-75.
作者姓名:李明静  庆伟霞  杨玉霞  赵东保  刘绣华  刘快之
作者单位:1. 河南大学,化学化工学院,河南,开封,475001
2. 河南大学,化学化工学院,河南,开封,475001;济源职业技术学院,河南,济源,454650
3. 河南大学,化学化工学院,河南,开封,475001;河南大学,天然产物与药物化学研究所,河南,开封,475001
摘    要:用单扫描示波极谱法研究了从东紫苏和黑沙蒿中分离出的七种黄酮类化合物对超氧阴离子自由基的清除作用.结果表明:七种黄酮类化合物清除O 2的作用强弱与它们所含酚羟基数目多少有关,羟基数目越多,对O 2清除的效果越好.C2-C3双键对黄酮类化合物清除O 2的活性也有贡献;糖苷因空间位阻效应而导致黄酮类化合物抗氧化能力下降.

关 键 词:黄酮  超氧阴离子  自由基  单扫描示波极谱法
文章编号:1008-1011(2006)04-0073-03
收稿时间:2006-07-07
修稿时间:2006年7月7日

Scavenging Activities of Seven Natural Flavonoids for Superoxide Anion Radicals
LI Ming-jing,QING Wei-xia,YANG Yu-xia,ZHAO Dong-bao,LIU Xiu-hua,LIU Kuai-zhi.Scavenging Activities of Seven Natural Flavonoids for Superoxide Anion Radicals[J].Chemical Research,2006,17(4):73-75.
Authors:LI Ming-jing  QING Wei-xia  YANG Yu-xia  ZHAO Dong-bao  LIU Xiu-hua  LIU Kuai-zhi
Abstract:Scavenging activities of seven natural flavonoids from elsholtzia bodinieri vaniot and artemisia ordosica kraschen for superoxide anion radicals was studied by single-sweep oscillopolarography. The results showed that the scavenging activities of the flavonoids for O2^- were related with the number of hydroxyl groups in the flavonoids. The more number of hydroxyl groups, the more active is the flavonoid. The C2-C3 double-bond is also contributed to scavenging O2^-. The glucoside of flavanone has reduced scavenging ability because of steric hindrance.
Keywords:flavonoids  superoxide anion  radical  single-sweep oscillopolarography
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