| 硼氢化钾还原肉桂醛合成肉桂醇的工艺研究 |
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| 引用本文： | 张付利,李宇熙,李省.硼氢化钾还原肉桂醛合成肉桂醇的工艺研究[J].化学研究,2012(1):89-91. |
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| 作者姓名： | 张付利 李宇熙 李省 |
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| 作者单位： | [1]河南大学医学院,河南开封475004 [2]河南大学药学院,河南开封475004 |
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| 摘 要： | 针对硼氢化钾还原肉桂醛制备肉桂醇的工艺,研究了反应物的物质的量之比、还原体系、反应时间、反应温度等因素对反应收率的影响.结果表明,在KBH4-THF-CH3CH2OH还原体系中,通过控制n(肉桂醛)∶n(硼氢化钾)=3∶1,在室温下反应1.5h,收率可达92.2%.
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| 关 键 词： | 硼氢化钾 还原 肉桂醛 肉桂醇 合成 |
Technology for synthesizing cinnamyl alcohol via reduction of cinnamaldehyde by potassium borohydride |
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| ZHANG Fu-li,LI Yu-xi,LI Sheng.Technology for synthesizing cinnamyl alcohol via reduction of cinnamaldehyde by potassium borohydride[J].Chemical Research,2012(1):89-91. |
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| Authors: | ZHANG Fu-li LI Yu-xi LI Sheng |
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| Institution: | 1. Medical College, Henan University, Kaifeng 475004, Henan, China; 2. Pharmaceutical College, Henan University, Kaifeng 475004, Henan, China) |
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| Abstract: | With a view to the technology for synthesizing cinnamyl alcohol via the reduction of cinnamaldehyde by potassium borohydride, we studied the effects of reactants molar ratio, reducing system, reaction time and reaction temperature on yield of the product. Results show that in the KBH4-THF-CH3CH2OH reduction system, cinnamyl alcohol can be synthesized from the reactants with a molar ratio of n（cinnamaldehyde） ： n（postassium borohydride） = 3 ： 1 in the yield of 92.2% after 1.5 h of reaction at room temperature. |
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| Keywords: | potassium borohydride reduction cinnamaldehyde cinnamyl alcohol synthesis |
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