| 取代苄基吡啶类季铵盐的制备及其杀菌活性 |
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| 引用本文： | 郑园,陈洁燕,黄东海,刘小平,杨乐敏,倪春林.取代苄基吡啶类季铵盐的制备及其杀菌活性[J].化学研究,2009,20(3):26-28. |
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| 作者姓名： | 郑园 陈洁燕 黄东海 刘小平 杨乐敏 倪春林 |
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| 作者单位： | 华南农业大学,理学院应用化学系,广东,广州,510642 |
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| 摘 要： | 采用吡啶或2-氨基吡啶与取代苄基衍生物反应获得3种苄基吡啶类季铵盐．即：溴化苄基吡啶盐（Bz—Py]Br），溴化苄基-2-氨基吡啶盐（Bz-2-NH2Py]Br）和溴化对硝基苄基吡啶盐（NO2Bzpy]Br]）．通过元素分析，红外光谱和电子喷雾质谱等手段进行了组成分析和结构表征，并以绿脓杆菌和金葡萄球菌为致病菌体测定了3种盐的杀菌活性．实验结果表明，所制备的3种吡啶类季铵盐具有良好的杀菌性能．
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| 关 键 词： | 吡啶类季铵盐 合成 杀菌活性 |
Syntheses and Antibacterial Properties of Substituted Benzyl Pyridine Quaternary Ammonium Salts |
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| ZHENG Yuan,CHEN Jie-yan,HUANG Dong-hai,LIU Xiao-ping,YANG Le-min,NI Chun-lin.Syntheses and Antibacterial Properties of Substituted Benzyl Pyridine Quaternary Ammonium Salts[J].Chemical Research,2009,20(3):26-28. |
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| Authors: | ZHENG Yuan CHEN Jie-yan HUANG Dong-hai LIU Xiao-ping YANG Le-min NI Chun-lin |
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| Institution: | (Department of Applied Chemistry, College of Science, South China Agricultural University, Guangzhou 510642, Guangdong, China) |
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| Abstract: | Three substituted benzyl pyridine quaternary ammonium salts,\Br,Bz-2-NH2Py]Br and NO2BzPy]Br,were synthesized by the reaction of pyridine or 2-aminopyridine and benzyl bromide or 4-nitrobenzyl bromide.Their components and structures were characterized by elemental analysis,infrared spectra,electronic spray mass spectra and conductivity.The antibacterial activities were measured by using blue-pus bacillus and aurococcus as pathogen.The experimental results indicated that the three salts exhibit good antibacterial properties. |
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| Keywords: | pyridine quaternary ammonium salts syntheses antibacterial properties |
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