110 keV Fe＋离子束对氨基酸衍生物的辐射分解

用200 kV离子注入机提供的110 keV Fe＋离子束注入L(＋)-半胱氨酸盐酸盐单晶水合物薄膜样品,离子注量为2.5×1016 ions?cm－2.离子注入后刮下薄膜进行简单固态混和,在傅里叶变换红外光谱仪、高效液相色谱仪和电喷雾电离-傅里叶变换质谱仪上对离子注入前后的样品分别进行了测试.对离子注入样品的两次红外光谱分析结果有所不同,表明薄膜样品不同部位受低能铁离子束辐照后可发生不同的辐射分解,但二者又具有一定的相似性,都反映了原分子中氨基、羧基和巯基等基团的受损和新的硝基的生成.高效液相色谱和傅里叶变换质谱分析表明,离子注入样品中产生了多种不同分子量的新分子,证实110 keV Fe＋离子束能够引起氨基酸衍生物的辐射分解.

Radiolysis of Amino Acid Derivatives Induced by the Irradiation of 110keV Fe+ Ion Beams

110 keV Fe＋ ion beams supplied by 200 kV ion injector were implanted into film samples of L(＋)-cysteine hydrochloride monohydrate. The dose was 2.5×1016 ions?cm-2.After the implantation, the film samples were scraped down and simply mixed together in the solid state. The samples before and after ion implantation were tested on FTIR, HPLC and ESI-FTMS spectroscope respectively. The two results of FTIR spectroscopic tests of the ion-implanted samples were different, which showed that radiolysis might have taken place at different sites of the film. But there is certain similarity between the two results in that they both showed the damages of the amino, carboxyl and sulfhydryl groups, and so on, of the original molecules and the formation of new nitro groups. The formation of many new molecules with various molecular weights was determined by HPLC and FTMS analysis and radiolysis of amino acid derivatives induced by the irradiation of 110 keV Fe＋ ion beams was confirmed.