| 线粒体体外代谢热动力学模型及其演化优化研究 |
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| 引用本文： | 熊亚,潘正君,王宏,吴鼎泉,康立山,屈松生.线粒体体外代谢热动力学模型及其演化优化研究[J].物理化学学报,1997,13(6):503-509. |
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| 作者姓名： | 熊亚 潘正君 王宏 吴鼎泉 康立山 屈松生 |
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| 作者单位： | Department of Chemistry,State Key Laboratory of Soft Engineer,Wuhan University,Wuhan 430072 |
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| 摘 要： | 导出了线粒体体外代谢的热动力学方程，探讨了它和指数模型的关系，将演化计算技术引入生物热化学领域，用ＭＴＤ方程和演化计算技术，对文献报导的八种鱼肝线粒体体外代谢的热动力学参数进行了全局优化。
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| 关 键 词： | 线粒体 演化计算 热动力学 全局优化 微量热 |
| 收稿时间： | 1996-09-22 |
| 修稿时间： | 1996-11-25 |
Studies on the Thermokinetic Model of Mitochondrial Metabolism and its Evolutionary Optimization |
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| XiongYa,Pan Zhengjun,Wang Hong,Wu Dingquan,Kang Lishan,Qu Songsheng.Studies on the Thermokinetic Model of Mitochondrial Metabolism and its Evolutionary Optimization[J].Acta Physico-Chimica Sinica,1997,13(6):503-509. |
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| Authors: | XiongYa Pan Zhengjun Wang Hong Wu Dingquan Kang Lishan Qu Songsheng |
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| Institution: | Department of Chemistry,State Key Laboratory of Soft Engineer,Wuhan University,Wuhan 430072 |
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| Abstract: | Thether mokinetic equation(MTD)of tochondrialmetabolism was educed and there lation between this equation and exponential model was ex amined.The technology of evo-lutionary computation was firstintr oducedto there sear chofbiological thermochemistry.The thermokineticp arameters of some mitochondrial external metabolism were globally optidrized with the evolution arycomputation program about MTD,which was programmed yourselves,and excellent result was obtained. |
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| Keywords: | Mitochondria Evolution computation Thermokinetics Global optimum Microcalorimetry |
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