| 磷酰化与非磷酰化蛋氨酸水溶液的脉冲辐解研究 |
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| 引用本文： | 储高升,张志成,张曼维,姚思德,王文锋,林念芸.磷酰化与非磷酰化蛋氨酸水溶液的脉冲辐解研究[J].物理化学学报,1996(12). |
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| 作者姓名： | 储高升 张志成 张曼维 姚思德 王文锋 林念芸 |
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| 摘 要： | 蛋氨酸能快速清除导致辐射损伤的·OH自由基，在放射生物学上是一类很重要的辐射保护剂，因此，引起了人们的广泛关注［l一到．生物大分子的磷酸化作用亦越来越受到重视，特别是近年来基因调控研究发现，许多蛋白质和生物酶只有被磷酸化氧化才具有生理活性，文献［4－6］报导蛋
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| 关 键 词： | 脉冲辐解 蛋氨酸 磷酰化蛋氨酸 α-氨基自由基 |
Pulse Radiolysis of Phosphoryl and Non-phosphoryl Methionine in Aqueous Solution |
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| Chu Gaosheng,Zhang Zhicheng,Zhang Manwei.Pulse Radiolysis of Phosphoryl and Non-phosphoryl Methionine in Aqueous Solution[J].Acta Physico-Chimica Sinica,1996(12). |
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| Authors: | Chu Gaosheng Zhang Zhicheng Zhang Manwei |
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| Abstract: | OH redical induced oxidation of methionine and N-phosphoryl methioninein aqueous solutions has been investigated using optical pulse radiolytical technique, theinfluence of N-phosphoryl group on the radiolytical processes of methionine has beenexplained by molecular structure and the rate constants of oxidation of N-phosphoryl methionine (NDM) by the OH radicals at different pH values have been determined. Thisresearch result suggests that the phosphonate ester has a coordinating effect on the radioprotection of methionine to the biological systems. |
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