首页 | 本学科首页   官方微博 | 高级检索  
     检索      

利用分子烙印技术分离中草药活性组分
引用本文:谢建春,骆宏鹏,朱丽荔,周力,李崇熙,徐筱杰.利用分子烙印技术分离中草药活性组分[J].物理化学学报,2001,17(7):582-585.
作者姓名:谢建春  骆宏鹏  朱丽荔  周力  李崇熙  徐筱杰
作者单位:College of Chemistry and Molecular Engineering,Peking University,Beijing 100871
基金项目:国家自然科学基金资助项目(29992590-2)
摘    要:用非共价法,在极性溶剂中,以丙烯酰胺作功能单体,以强极性化合物槲皮素为模板 ,制备了分子烙印聚合物(MIP). 液相色谱实验表明, MIP 对槲皮素具有特异的亲合性.将此 MIP直接分离银杏叶提取物水解液, 得到主要含模板槲皮素及与槲皮素结构相似化合物山奈 酚两种黄酮的组分.研究证实了MIP技术用于直接分离、提取中草药中具有特定药效化合物的 可行性.

关 键 词:分子烙印  槲皮素  山奈酚  银杏叶  丙烯酰胺  
收稿时间:2001-04-04
修稿时间:2001年4月4日

Extracting Active Compounds from Herbs Using Molecular Imprinting Technology
Xie Jian-Chun Luo Hong-Peng Zhu Li-Li Zhou Li Li Chong-Xi Xu Xiao-Jie.Extracting Active Compounds from Herbs Using Molecular Imprinting Technology[J].Acta Physico-Chimica Sinica,2001,17(7):582-585.
Authors:Xie Jian-Chun Luo Hong-Peng Zhu Li-Li Zhou Li Li Chong-Xi Xu Xiao-Jie
Institution:College of Chemistry and Molecular Engineering,Peking University,Beijing 100871
Abstract:A molecularly imprinted polymer (MIP) was prepared using quercetin as the template and acrylamide as the hydrogen-bonding functional monomer in a polar solvent. The polymer exhibited high affinity for quercetin and good selectivity among the tested compounds. And when it was used as an extraction cartridge for the hydrolyzate of gingko leaves,it can purify the flavonoid component in the hydrolyzate,catching mainly quercetin and kaempferol. Thus it demonstrated the feasibility of using MIP in extracting specific pharmacophoric compounds directly from herbs.
Keywords:Molecularly imprinted polymer  Quercetin  Kaempferol  Gingko  Acrylamide
本文献已被 CNKI 维普 万方数据 等数据库收录!
点击此处可从《物理化学学报》浏览原始摘要信息
点击此处可从《物理化学学报》下载免费的PDF全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号