Applications of a Technique for the HPLC Analysis of Liquid Carbon Dioxide Solutions

Abstract

A novel technique has been developed whereby substrate and solvent quantitation can be effected by means of reversed-phase high performance liquid chromatography. Carbon dioxide is detected by a differential refractometer.

Applications of this technique include the analysis of liquefied carbon dioxide-based aerosol mixtures, solubility measurements and liquid carbon dioxide extraction studies. Preliminary experiments suggest that this technique may also find application to the direct analysis of supercritical carbon dioxide extraction systems.