基于有序介孔碳的氯离子选择性电极的制备及其在手持传感系统中的应用

以有序介孔碳(OMC)球为离子-电子转换层,制备了固态氯离子选择性电极,构建了基于离子敏感的场效应晶体管(ISFET)的手持式传感系统,用于检测人体血清中的氯离子。优化了OMC前驱体的碳化温度,探究了OMC形貌结构对电极传感性能的影响;电极柔性化制备后考察了其在手持系统中对氯离子的检测效果。结果表明,最优条件下,电极在5.12×10^-4~1.02 mol/L的浓度范围呈现线性响应,响应斜率为60 mV/decade。该柔性电极在手持传感系统中展现出高灵敏度和重现性,可用于人体血清样品中氯离子的检测,其回收率为96.3%~104.9%。

Preparation of ordered mesoporous carbon sphere based chloride-ion selective electrode and its application for handheld sensing system

All-solid-state chloride ion-selective electrodes were prepared using ordered mesoporous carbon(OMC)sphere as ion-electron transducer.Provided with ion-sensitive field-effect transistor(ISFET)based handheld Cl-sensing system,the flexible ISEs were further applied for the detection of chloride in human serum sample.The morphology and structure of OMC were optimized by adjusting the temperatures of the thermal treatment,and the corresponding ion-electron transduce ability was also investigated.The sensing performance of flexible ISEs in the handheld Cl-sensing system was measured.The optimization results indicated that the electrode showed a stable potential response with slope of 60 m V/dec in the linear range of 5.12×10^-4-1.02 mol/L.More importantly,the flexible ISEs in handheld Cl-sensing system showed high sensitivity and reproducibility,and recoveries were from 96.3%to 104.9%in human serum samples tests.