顺二醇类生物分子的硼亲和分子印迹研究进展EI北大核心CSCD

含顺二酚的分子,如糖类、糖苷和糖蛋白等,在糖组学、代谢组学和蛋白质组学等不同领域都有着至关重要的作用。但是这类样品分子通常存在于非常低丰度的环境中且与许多干扰化合物共存,给临床和生物学上的分离检测带来了巨大的困难。因此,开发建立对顺二醇类化合物简单高效的分离方法具有重要意义。分子印迹技术,是基于模拟生物体内抗原与抗体相互作用原理而发展起来的一种新兴技术,近年来因其特定的分子识别能力以及材料的稳定性和重复性而引起了广泛关注,也在顺二醇类化合物的分离方面得到了许多应用。本综述总结了在顺二醇类化合物的分子印迹方面的最新进展,并对其未来发展的方向和前景进行了讨论。

Advances in boron affinity molecular imprinting of cis-diol-containing biomolecules

Cis-diol containing compounds, such as saccharides, glycosides, and glycoproteins, play a vital role in the diverse fields of glycomics, metabolomics and proteomics. However, this kind of sample molecules usually exist in very low abundance environments and also co-exist with many interfering compounds, which brings great difficulties for clinical or biological isolation and detection. Therefore, it is of great significance to develop a simple and efficient separation method for cis-diol compounds. Molecular imprinting technology is a new technology developed based on the principle of simulating the interaction between antigens and antibodies. In recent years, it has attracted wide attention due to its specific molecular recognition ability, stability and repeatability. It has also been widely applied in the separation of cis-diol compounds. In this review, the latest advances in molecular imprinting of cis-diol compounds are summarized, and the future development of cis-diol compounds is also discussed. © 2022, Youke Publishing Co.,Ltd. All rights reserved.