GC-MS/MS法测定沉积物和生物样品中邻苯二甲酸酯

采用固相萃取(SPE)和QuEChERS技术结合气相色谱-串联质谱(GC-MS/MS)技术,建立了养殖海域沉积物和生物样品中16种邻苯二甲酸酯(PAEs)定量分析方法.沉积物样品以二氯甲烷为提取溶剂,经PSA-Silica固相萃取柱净化,生物样品以乙腈为提取溶剂,经150.0 mg N-丙基乙二胺(PSA)、150.0...

Determination of phthalate esters in sediments and biological samples by GC-MS/MS

A precise quantitative analysis method for phthalate esters(PAEs)detection in sediments and biological samples was established using solid phase extraction(SPE)and QuECHERS combined with GC-MS/MS.The sediment samples were extracted with dichloromethane and purified using N-propyl ethanediamine(PSA)-Silica SPE column.The biological samples were extracted with acetonitrile and purified with 150.0 mg PSA,150.0 mg C18 and 150.0 mg graphitized carbon black(GCB).The quantitative analysis was carried out under multi-reaction monitoring mode(MRM).The results showed that linear correlation 16 PAEs was good in the concentration range of 0.5-300μg/L(R²>0.9990).The limits of detection(LODs)of sediment samples were in the range of 0.10-1.54μg/kg,and the average recoveries were 70.1%-110.2%with relative standard deviations(RSDs)of 2.9%-7.9%at three adding concentrations of 10.0,20.0 and 50.0μg/L.For biological samples,LODs ranged from 0.23 to 0.96μg/kg,and the average recoveries were between 71.8%and 107.4%,with RSDs in the range of 2.6%-9.1%.The method is suitable for the monitoring of PAEs in sediments and organisms in marine environment.