基于表面增强拉曼光谱技术对医疗美容产品中正壬酸香草酰胺的快速检测

以银纳米线为拉曼基底,运用表面增强拉曼光谱技术(SERS)建立了对发热剂中正壬酸香草酰胺的检测方法。采用简便有效的两步滴加多元醇法制备了具有SERS活性的银纳米线,利用扫描电镜和紫外-可见光谱仪对银纳米线进行了表征。对正壬酸香草酰胺进行了SERS研究并对正壬酸香草酰胺的SERS谱带进行了归属。正壬酸香草酰胺的质量浓度在1~1.0×10^-8mg/L范围内与其在1588 cm^-1处的SERS特征峰强度有良好的线性关系,方法的最低检出浓度可达0.66 pg/L。对样品进行前处理后,运用加标回收法考察其回收率。该方法可以用于发热剂中正壬酸香草酰胺的检测。

Rapid detection of nonivamide in medical beauty products based on surface enhanced Raman spectroscopy

A surface-enhanced Raman(SERS) analytical method based on silver nanowires as Raman substrates has been established for the determination of nonivamide in medical beauty products.SERS active silver nanowires were prepared by a facile and effective two-step dropwise addition polyol method,and were characterized by scanning electron microscopy and UV-Vis spectroscopy.Silver nanowires were chosen as SERS substrates to detect trace nonivamide and the SERS peaks were assigned.Under the optimized conditions,the linear regression equation was established between the concentration of nonivamide residues and the peak intensity when the concentration range of nonivamide residues was 1-1.0 × 10^-8 mg/L.After the sample treatment,the recoveries were investigated by standard addition recovery method.This method can be used for the detection of nonivamide in heating agents.