| 用组合化学建立天然产物类似物库 |
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| 引用本文： | 张城,李伟章,恽榴红.用组合化学建立天然产物类似物库[J].化学进展,2003,15(3):194-203. |
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| 作者姓名： | 张城 李伟章 恽榴红 |
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| 作者单位： | （军事医学科学院毒物药物研究所 北京 100850） |
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| 摘 要： | 天然产物是药物先导化合物的重要来源.组合化学技术在天然产物的研究中起着越来越重要的作用.目前已构建并合成了许多以天然产物为模板的化合物库,为基于天然产物的药物研究开辟了广阔的空间.
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| 关 键 词： | 组合化学 天然产物 化合物库 |
| 文章编号： | 1005-281X(2003)03-0194-10 |
| 收稿时间： | 2002-06-01 |
| 修稿时间： | 2002年6月1日 |
Application of the Combinatorial Chemistry to Research of the Natural Products |
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| Zhang Cheng,Li Weizhang,Yun Liuhong.Application of the Combinatorial Chemistry to Research of the Natural Products[J].Progress in Chemistry,2003,15(3):194-203. |
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| Authors: | Zhang Cheng Li Weizhang Yun Liuhong |
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| Institution: | (Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850, China) |
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| Abstract: | Natural products are one of the most important sources of the lead compounds in drug discovery. Combinatorial chemistry is now playing important role in the research of the natural products. In recent years, a number of molecular libraries have been designed and synthesized based on natural templates and they will provide a useful method for the development of the drug research based on the natural products. |
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| Keywords: | combinatorial chemistry natural products compound libraries |
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