| 三维定量结构-活性关系研究的近况 |
| |
| 引用本文： | 孙红梅,谢前.三维定量结构-活性关系研究的近况[J].化学进展,1996,8(1):79-85. |
| |
| 作者姓名： | 孙红梅 谢前 |
| |
| 作者单位： | （中国科学院化工冶金研究所计算机化学开放实验室 北京 100080） |
| |
| 摘 要： | 本文介绍并综述了以CoMFA, APEX-3D, Ludi和Leapfrog为代表的三维定量结构一活性关系研究方法的近况。作为药物分子设计的新方法，它们在新药设计和先导化合物的产生中起着越来越重要的作版。
|
| 关 键 词： | 三维定量结构-活性关系 CoMFA APEX-3D Ludi Leapfrog |
| 收稿时间： | 1995-03-01 |
Progress on 3D-QSAR Research |
| |
| SunHongmei,Xie Qian,Zhou Jiaju,Xu Zhihong.Progress on 3D-QSAR Research[J].Progress in Chemistry,1996,8(1):79-85. |
| |
| Authors: | SunHongmei Xie Qian Zhou Jiaju Xu Zhihong |
| |
| Institution: | (Laboratory of Computer Chemistry, Chinese Academy of Sciences, Beijing 100080) |
| |
| Abstract: | The recent development of the 3D-QSAR research has been reviewed, includingCoMFA, APEX-3D, Ludi and Leapfrog. All these methods are 3D computer-aided melocular design commercial softwares. They are playing more and more important role in desinging new drugs and finding lead compounds. |
| |
| Keywords: | 3D-QS AR CoMFA APEX-3D Ludi Leapfrog |
| 本文献已被 维普 等数据库收录！ |
| 点击此处可从《化学进展》浏览原始摘要信息 |
| 点击此处可从《化学进展》下载免费的PDF全文 |
