Platycoside N: a new oleanane-type triterpenoid saponin from the roots of Platycodon grandiflorum |
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Authors: | Li Wei Zhang Wei Xiang Lan Wang Zi Zheng Yi-Nan Wang Ying-Ping Zhang Jing Chen Li |
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Institution: | College of Chinese Material Medicine, Jilin Agricultural University, Changchun 130118, China. liwei7727@126.com |
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Abstract: | A new oleanane-type triterpenoid saponin, named platycoside N (1), together with six known saponins, was isolated from the roots of Platycodon grandiflorum. On the basis of acid hydrolysis, comprehensive spectroscopic data analyses and comparison with the spectral data of the known compounds, its structure was elucidated as 3-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl-2β,3β,16α,23-tetrahydroxyolean-12-en-28-oic acid 28-O-β-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranoside. The six known compounds were platycodin D (2), deapioplatycodin D (3), platycodin D3 (4), deapioplatycodin D3 (5), platycoside E (6) and deapioplatycoside E (7). |
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