Platycoside O, a new triterpenoid saponin from the roots of Platycodon grandiflorum |
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Authors: | Fu Wen-Wei Fu Jin-Nan Zhang Wen-Meng Sun Li-Xin Pei Yue-Hu Liu Ping |
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Institution: | Institute of Liver Diseases, Shanghai Shuguang Hospital, Shanghai 201203, China. fuwenwei@yahoo.com |
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Abstract: | A new unusual minor triterpenoid saponin, platycoside O (1), was isolated from the 75% EtOH extract obtained from the roots of Platycodon grandiflorum, together with four known saponins: platycoside M-3 (2), platycoside J (3), platycoside F (4) and platycoside B (5). The structure of 1 was determined as 3-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl-2β,3β,16α,23-tetrahydroxyolean-12-en-24-methoxyl, 24-oxo-28-oic acid 28-O-β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranoside on the basis of spectral analysis and chemical evidence. |
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