Spectroscopic Investigation of Polypeptide Plane Brushes |
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| Authors: | Elena Vlasova Boris Volchek Irina Tarasenko Guennadii Vlasov |
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| Institution: | Institute of Macromolecular Compounds, Russian Academy of Sciences, 199004, St. Petersburg, Bol'shoi prospect 31, Russia |
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| Abstract: | Fourier transform infrared spectroscopy (FTIR) was used for determination of orientational and conformational characteristics of plane polypeptide brushes with different density of polypeptide chains grafted to modified silicon surface. The determination of grafting density of polypeptide chains in brushes, which depends on chemical structure of spacer groups, was carried out using ultraviolet (UV) spectroscopy. The influence of chemical structure of modifying spacer groups and outer conditions on the characteristics of plane polypeptide brushes was established. The peculiarities of α-helical structure (random coil transfer of polymer chains in brushes under the action of denaturants) were investigated. |
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| Keywords: | FTIR monolayers orientation polymer brushes polymer chain |
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