Palladium‐catalyzed Suzuki–Miyaura coupling with aryl and heteroaryl bromides using N,N,N′,N′‐tetra(diphenylphosphinomethyl)‐1,2‐ethylenediamine |
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| Authors: | Kun Wang Tao Yi Xiaojun Yu Xueli Zheng Haiyan Fu Hua Chen Ruixiang Li |
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| Institution: | Key Laboratory of Green Chemistry and Technology, Ministry of Education, Department of Chemistry, Sichuan University, , Chengdu,, Sichuan, 610064 People's Republic of China |
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| Abstract: | An easily prepared tetraphosphine N,N,N′,N′‐tetra(diphenylphosphinomethyl)‐1,2‐ethylenediamine (1) combined with PdCl2 affords an efficient catalytic system for Suzuki cross‐coupling of aryl and heteroaryl bromides. A high turnover number of 750 000 is obtained with the catalyst loading as low as 1 ppm. This catalyst system exhibits good stability and longevity. In this study, a broad scope of substrates is investigated and satisfactory yields are obtained. Copyright © 2012 John Wiley & Sons, Ltd. |
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| Keywords: | Suzuki– Miyaura coupling palladium tetraphosphine |
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