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Synthesis of heterobiaryls via Suzuki‐Miyaura coupling reaction of potassium aryltrifluoroborates with heteroaryl halides in aqueous systems |
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| Authors: | Leifang Liu Kai Zhao Wenbo Li Mingli Liu Yuting Chen Yan Dong |
| Abstract: | A variety of heterobiaryl compounds have been synthesized by the Suzuki‐Miyaura coupling reactions of heteroaryl halides with potassium aryltrifluoroborates. Pd (OAc)2 was found to be highly efficient for the Suzuki‐Miyaura coupling reactions of various heteroaryl halides with potassium aryltrifluoroborates in aqueous systems, delivering the corresponding heterobiaryl compounds in good to excellent yields. |
| Keywords: | aqueous system heteroaryl halide heterobiaryl compound potassium aryltrifluoroborate Suzuki‐Miyaura coupling reaction |