| 崩解时限测试标准物质的研制 |
| |
| 引用本文： | 艾明泽,肖哲.崩解时限测试标准物质的研制[J].化学分析计量,2011,20(4):4-6. |
| |
| 作者姓名： | 艾明泽 肖哲 |
| |
| 作者单位： | 辽宁省计量科学研究院,沈阳,110004 |
| |
| 摘 要： | 以乳糖、淀粉、羟丙甲基纤维素、水、硬酯酸镁和羧甲基淀粉钠为主要原料,经筛选、按量称取混合、制粒干燥及压片制成崩解时限测试标准物质.均匀性和稳定性检验结果表明,研制的标准物质均匀性良好,稳定时间为12个月.通过多家实验室定值,定值结果为472 s,扩展不确定度为58 s(k=2).
|
| 关 键 词： | 崩解时限测试标准物质 均匀性 稳定性 定值 |
RESEARCH ON REFERENCE MATERIAL FOR DISINTEGRATION TEST |
| |
| Ai Mingze,Xiao Zhe.RESEARCH ON REFERENCE MATERIAL FOR DISINTEGRATION TEST[J].Chemical Analysis And Meterage,2011,20(4):4-6. |
| |
| Authors: | Ai Mingze Xiao Zhe |
| |
| Institution: | Ai Mingze,Xiao Zhe(Liaoning Provincial Institute of Measurement,Shenyang 110004,China) |
| |
| Abstract: | The reference material consisted of lactose,starch,HPMC,water,sodium stearate and CMS was developed for disintegration test.The preparation process inculded screening,mixture,granulation,drying and tableting.The unifomity and stability test indicated that the reference material had fine unifomity and stability.Muti-laboratories certification result was 472 s with expanded uncertainty of 58 s(k=2). |
| |
| Keywords: | reference materials for disintegration test unifomity stability cetification |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
