| 白血病细胞内磷酸单酯的31P核磁共振分析 |
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| 引用本文： | 黄荣清,舒融,颜贤忠,骆传环,杜泽涵.白血病细胞内磷酸单酯的31P核磁共振分析[J].分析测试学报,2002,21(4):5-7. |
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| 作者姓名： | 黄荣清 舒融 颜贤忠 骆传环 杜泽涵 |
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| 作者单位： | 1. 军事医学科学院放射医学研究所,北京,100850
2. 军事医学科学院国家生物医学分析中心,北京,100850 |
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| 基金项目： | 国家自然科学基金资助项目 (29905005)，北京市自然科学基金资助项目 (7002029) |
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| 摘 要： | 对人早幼粒白血病细胞HL－60和人淋巴瘤白血病细胞Molt-4的^31P NMR谱进行了分析，HL－60和Molt-4细胞显示很强的磷酸单酯峰，磷酸单酯峰中包含有磷酸胆碱和磷酸乙醇胺；并进一步对磷酸单酯峰的特征及形成进行了分析；结果提示可能根据磷酸单酯峰的特征对癌进行诊断和分析。
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| 关 键 词： | 白血病 细胞 核磁共振 磷酸单酯 诊断 |
| 文章编号： | 1004-4957(2002)04-0005-03 |
| 修稿时间： | 2002年2月9日 |
Analysis of Phosphomonoesters in Leukemic Cell Lines by 31P Nuclear Magnetic Resonance |
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| HUANG Rong- qing,SHU Rong,YAN Xian- zhong,LUO Chuan- huan,DU Ze- han.Analysis of Phosphomonoesters in Leukemic Cell Lines by 31P Nuclear Magnetic Resonance[J].Journal of Instrumental Analysis,2002,21(4):5-7. |
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| Authors: | HUANG Rong- qing SHU Rong YAN Xian- zhong LUO Chuan- huan DU Ze- han |
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| Institution: | HUANG Rong- qing1,SHU Rong1,YAN Xian- zhong2,LUO Chuan- huan1,DU Ze- han2 |
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| Abstract: | P nuclear magnetic resonance spectroscopy was used for the analysis phosphorus containing compounds in human lymphoma leukemia cell line Molt- 4 and human promyelocyte leukemia cell line HL- 60. As compared with nontumorous cells the two leukemic cells have a strong phosphomonoester peak. The character and formation of the peak were discussed. The phosphomonoester peak was composed of two peaks of phosphoethanolamine and phosphocholine. The results indicated possibility for clinical diagnosis and analysis of tumor based on the phosphomonoester peak. |
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| Keywords: | P NMR Lymphoma leukemia cell Promyelocyte leukemia cells Phosphomonoester |
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