顶空/气相色谱-质谱法测定圆珠笔中8种挥发性苯系物

建立了顶空/气相色谱-质谱法测定圆珠笔中8种挥发性苯系物(苯、甲苯、乙苯、对二甲苯、间二甲苯、异丙苯、邻二甲苯和苯乙烯)含量的分析方法。选择顶空平衡温度和时间分别为70℃和40min,以HP-INNOWax色谱柱(60m×320μm×0.25μm)分离,采用选择离子监测模式(SIM)检测,外标法定量。结果显示,8种苯系物在0.005~0.5mg/L质量浓度范围内均与对应的峰面积呈良好的线性关系(r^2>0.999),检出限(S/N=3)为0.01~0.02mg/kg,加标回收率为86.0%~104%,相对标准偏差(RSD)为2.3%~9.6%。该方法操作简单,快速,且灵敏度高,适用于圆珠笔中挥发性苯系物的快速检测。

Determination of Eight Volatile Benzene Homologues in Ball-point Pen by Headspace Gas Chromatography-Mass Spectrometry

A method of headspace gas chromatography-mass spectrometry (HS/GC-MS ) was developed for the determination of eight volatile benzene homologues,i.e.benzene,toluene,ethylbenzene, p -xylene, m - xylene,isopropylbenzene, o -xylene and styrene in ball-point pen.The equilibrium temperature and time for headspace sampler were set at 70 ℃ and 40 min,respectively.The analytes were separated on an HP-INNOWax column (60 m×320 μm×0.25 μm ),then detected in selected-ion monitoring mode and quantified by external standard method.Results showed that the standard curves for eight benzene homologues were linear over the concentration range of 0.005-0.05 mg/L with the linear correlation coefficients greater than 0.999.The detection limits of the method ( S/N =3 ) were in the range of 0.01-0.02 mg/kg.The spiked recoveries ranged from 86.0 % to 104 % with RSDs of 2.3 %-9.6 %.The method is simple,rapid and high sensitive,and is suitable for the determination of volatile benzene homologues in ball-point pen.