首页 | 本学科首页   官方微博 | 高级检索  
     检索      

蜂蜜中链霉素与双氢链霉素残留量的液相色谱串联质谱法测定
引用本文:刘晓茂,赵淑军,张进杰,曹亚平,张守军,孙海侠.蜂蜜中链霉素与双氢链霉素残留量的液相色谱串联质谱法测定[J].分析测试学报,2008,27(12).
作者姓名:刘晓茂  赵淑军  张进杰  曹亚平  张守军  孙海侠
作者单位:1. 秦皇岛出入境检验检疫局,河北,秦皇岛,066002
2. 河北大学化学与环境科学学院,河北,保定,071002
摘    要:建立了液相色谱串联质谱(HPLC-MS/MS)同时对蜂蜜中链霉素和双氢链霉素残留量进行分析的方法。采用磷酸溶液提取,苯磺酸固相萃取柱和C18固相萃取柱串联净化,液相色谱串联质谱测定。链霉素的检出限为0.002 mg/kg,线性范围为0.005~0.100 mg/kg,相关系数为0.9992;双氢链霉素检出限为0.001mg/kg,线性范围为0.002~0.050 mg/kg,相关系数为0.9924。方法回收率为78%~95%,相对标准偏差为2.6%~4.9%。该法实用、准确、快捷,可应用于蜂蜜样品中链霉素和双氢链霉素的同时检测。

关 键 词:液相色谱-串联质谱  蜂蜜  链霉素  双氢链霉素  残留

Simultaneous Determination of Streptomycin and Dihydrostreptomycin Residues in Honey by HPLC-MS/MS
LIU Xiao-mao,ZHAO Shu-jun,ZHANG Jin-jie,CAO Ya-ping,ZHANG Shou-jun,SUN Hai-xia.Simultaneous Determination of Streptomycin and Dihydrostreptomycin Residues in Honey by HPLC-MS/MS[J].Journal of Instrumental Analysis,2008,27(12).
Authors:LIU Xiao-mao  ZHAO Shu-jun  ZHANG Jin-jie  CAO Ya-ping  ZHANG Shou-jun  SUN Hai-xia
Abstract:A HPLC-MS/MS method was developed for simultaneous determination of streptomycin and dihydrostreptomycin residues in honey sample.The samples were extracted by phosphoric acid,and cleaned up by aromatic sulfonic and C18 solid phase extraction column,respectively.The target compounds were qualitatively and quantitatively determined by HPLC-MS/MS.The calibration curve showed a good linearity in the range of 0.005-0.100 mg/kg for streptomycin with a correlation coefficient of 0.999 2,and 0.002-0.050 mg/kg for ...
Keywords:HPLC-MS/MS  honey  streptomycin  dihydrostreptomycin  residues  
本文献已被 CNKI 维普 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号