Photochemical stability of collagen/poly(ethylene oxide) blends |
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| Institution: | 1. Departamento de Ingeniería Química, Universidad Nacional del Sur e Instituto de Ing. Electroquímica y Corrosión (INIEC), Av. Alem 1253, 8000 Bahía Blanca, Argentina;2. Departamento de Física, Universidad Nacional del Sur & IFISUR (UNS – CONICET), Av. Alem 1253, 8000 Bahía Blanca, Argentina;1. Department of Pharmacology and Toxicology, Virginia Commonwealth University, 410 North 12th Street, PO Box 980613, Richmond, VA 23298-0613, United States;2. Department of Medicinal Chemistry, Virginia Commonwealth University, BioTech One, Suite 205, 800 E. Leigh St., PO Box 980540, Richmond, VA 23298-0540, United States;1. Departments of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA;2. Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA;3. Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA;4. Anesthesiology, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA |
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| Abstract: | The photochemical stability of the blends of collagen and poly(ethylene oxide) PEO has been studied by Fourier transform infrared spectroscopy (FTIR), UV–vis spectroscopy and viscosimetry. Surface properties before and after UV irradiation were observed using an optical microscope.Collagen and PEO were immiscible in diluted solution and only small interactions between the two components in the solid state were observed. New materials based on the blending of collagen and PEO that we obtained have a different photochemical stability than those of single components. In general, collagen/PEO blends are less stable under UV irradiation than pure collagen. The influence of PEO on the photochemical stability of collagen depends on the concentration of this polymer in the blend. Microscopic photographs show that the surface characteristics of thin films of collagen/PEO blends are not drastically altered after UV irradiation. |
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