| 2,3—二甲基吡嗪合成工艺的改进 |
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| 引用本文： | 李谦和,尹笃林.2,3—二甲基吡嗪合成工艺的改进[J].合成化学,1997,5(2):189-192. |
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| 作者姓名： | 李谦和 尹笃林 |
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| 作者单位： | 湖南师范大学精细催化合成研究所 |
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| 摘 要： | 报道了以丁二酮和乙二胺为原料，对液相合成２，３－二甲基吡嗪的方法进行了改进，考察了反应温度，溶剂用量和脱氢剂等对反应影响，确定了合成２，３－二甲基吡嗪的优化条件为，丁二酮：乙二胺（摩尔比）＝１：１．０５；丁二酮：溶剂无水乙醇（体积比）＝１：１０，缩合反应温度：－５℃，时间：１ｈ，脱氢剂：ＤＨＫＭ－１２，脱氢温度：８０～８５℃，时间：１ｈ２，３－二甲基吡嗪的产率按投料丁二酮设计达６５％。
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| 关 键 词： | 2 3－二甲基吡嗪 乙二胺 丁二酮 食用香料 合成 |
Improved Synthesis of N benzyl N ethylaniline |
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| Li,Ying Cheng Hu,Yu Qiao Li,Gong Ben Yuan,Yun Cheng Jiang,Yu Lin.Improved Synthesis of N benzyl N ethylaniline[J].Chinese Journal of Synthetic Chemistry,1997,5(2):189-192. |
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| Authors: | Li Ying Cheng Hu Yu Qiao Li Gong Ben Yuan Yun Cheng Jiang Yu Lin |
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| Abstract: | It is reported that N ethylaniline could be efficiently synthesized from aniline and ethanol in the presence of Raney Ni, and N benzyl N ethyl aniline could be conveniently prepared from N ethylaniline and benzyl chloride with the phase transfer catalyst. The yield of the first synthesis is about 30% more than that reported in the classical method. |
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| Keywords: | N benzyl N ethylaniline Raney Ni PTC Aniline N ethylaniline |
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