pH敏感性两亲聚合物网络PAA—l—PTHF的研究

以具有良好柔性和生物相容性的聚四氢呋喃（ＰＴＨＦ）为疏水链段，具有ｐＨ敏感性的聚丙烯酸（ＰＡＡ）为亲水链段，通过ＰＴＨＦ双端基大分子单体与丙烯酸自由基共聚，首次合成了聚丙烯酸－ｌ－聚四氢呋喃（ＰＡＡ－ｌ－ＰＴＨＦ）两亲聚合物网络，并对网络的结构、组成以及交联点密度进行了表征。两亲聚合物网络溶胀行为研究表明，ＰＡＡ－ｌ－ＰＴＨＦ既能在水中溶胀又能在有机溶剂中溶胀，在水中的溶胀度随网络亲水链段ＰＡＡ含

pH-Sensitive Poly(acrylic acid)-l- polytetrahydrofuran Amphiphilic Polymer Network

A series of novel poly(acrylic acid) l polytetrahydrofuran (PAA l PTHF) amphiphilic networks were synthesized by free radical copolymerization of hydrophobic polytetrahydrofuran diacrylate macromonomer with hydrophilic acrylic acid. Their structure and composition have been characterized and the swelling behaviors of these networks were studied. The amphiphilic nature of them is substantiated by swelling data. They swell in both hydrophilic and hydrophobic solvents and the swelling ratio changes significantly with network composition, which increased with increasing of hydrophilic content of networks in water. The swelling behavior of networks in different solvents exhibits not only the properties of both hydrophilic and hydrophobic segments, but also the combined properties of the two segments. These amphiphilic networks exhibit different swelling process in hydrophilic solvents and hydrophobic solvents, and show pH sensitive swelling in aqueous media.