| Pd(OAc)_2/TBAB催化卤代芳烃与末端炔烃的Sonogashira交叉偶联反应研究 |
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| 引用本文： | 陶李明,刘文奇,周芸.Pd(OAc)_2/TBAB催化卤代芳烃与末端炔烃的Sonogashira交叉偶联反应研究[J].合成化学,2010,18(2). |
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| 作者姓名： | 陶李明 刘文奇 周芸 |
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| 作者单位： | 湘南学院,化学与生命科学系,湖南,郴州,423000 |
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| 基金项目： | 湖南省自然科学基金，湖南省教育厅资助项目 |
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| 摘 要： | 研究了无铜、无配体、可回收利用的催化体系Pd(OAc)2/TBAB]催化卤代芳烃与末端炔烃的Sonogashira交叉偶联反应,高产率地合成了一系列偶联产物,其结构经1H NMR和13C NMR表征。催化实验结果表明,Pd(OAc)2/TBAB可回收重复使用3次,催化活性基本不变。
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| 关 键 词： | 溴化四丁基铵 醋酸钯 Sonogashira交叉偶联反应 合成 催化体系 |
Study on the Sonogashira Cross-couplings of Aryl Halides with Terminal Alkynes by Pd(OAc)_2/TBAB |
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| TAO Li-ming,LIU Wen-qi,ZHOU Yun.Study on the Sonogashira Cross-couplings of Aryl Halides with Terminal Alkynes by Pd(OAc)_2/TBAB[J].Chinese Journal of Synthetic Chemistry,2010,18(2). |
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| Authors: | TAO Li-ming LIU Wen-qi ZHOU Yun |
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| Abstract: | Sonogashira cross-couplings of aryl halides with terminal alkynes were investigated using copper-free, ligand-free and reusable Pd(OAc)_2/TBAB as the catalyst. A series of coupling compounds were synthesized in high yields. The structures were characterized by ~1H NMR and ~(13)C NMR. Pd(OAc)_2/TBAB could be recovered and reused three times without a loss of catalytic efficiency. |
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| Keywords: | TBAB Pd(OAc)_2 Sonogashira cross-coupling reaction synthesis catalyst system |
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