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Combined QSAR studies of inhibitor properties of O-phosphorylated oximes toward serine esterases involved in neurotoxicity,drug metabolism and Alzheimer's disease |
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| Authors: | GF Makhaeva EV Radchenko II Baskin VA Palyulin NS Zefirov |
| Institution: | 1. Institute of Physiologically Active Compounds , Chernogolovka , Moscow Region , Russia;2. Institute of Physiologically Active Compounds , Chernogolovka , Moscow Region , Russia;3. Department of Chemistry , Moscow State University , Moscow , Russia |
| Abstract: | |
| Keywords: | anti-Alzheimer drugs comparative molecular similarity index analysis (CoMSIA) molecular field topology analysis (MFTA) phosphorylated oxime (POX) quantitative structure-activity relationships (QSAR) serine esterases |