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Synthesis of Enantiomeric Aminophosphonic Acids and Peptides |
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| Authors: | Valery Kukhar Vladimir Solodenko Vadim Soloshonok Tamara Kasheva |
| Abstract: | Abstract Synthesis of enantiomeric amino phosphonic acids APA is described by using chiral auxiliary reagent or enzymatic resolution of racemic mixtures of APA phenacyl derivatives. Peptides with APA residue were obtained by application of trimethylsilyl derivatives or condensation in the presence of enzyme-papain |
| Keywords: | aminophosphonic acids enantiomers peptides enzymes |