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Furo[3,2-h]isochroman, furo[3,2-h]isoquinoline, isochroman, phenol, pyranone, and pyrone derivatives from the sea fan-derived fungus Penicillium sp. PSU-F40
Authors:Kongkiat Trisuwan  Yaowapa Sukpondma  Sita Preedanon
Institution:a Department of Chemistry and Center for Innovation in Chemistry, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand
b Natural Products Research Center and Department of Microbiology, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand
c National Center for Genetic Engineering and Biotechnology (BIOTEC), Thailand Science Park, Klong Luang, Pathumthani 12120, Thailand
Abstract:Nine new fungal metabolites, penicisochromans A-E, penicipyrone, penicipyranone, peniciphenol, and penicisoquinoline, were isolated from the sea fan-derived fungus Penicillium sp. PSU-F40 together with five known compounds. Their structures were determined by spectroscopic analysis. Their antibacterial activity against the standard Staphylococcus aureus ATCC 25923 and methicillin-resistant S. aureus was evaluated.
Keywords:Sea fan-derived fungus  Penicillium sp    Furo[3  2-h]isochroman  Furo[3  2-h]isoquinoline
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