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Highly efficient synthesis of triazolo[1,2-a]indazole-triones and novel spiro triazolo[1,2-a]indazole-tetraones under solvent-free conditions
Authors:Alireza Hasaninejad  Abdolkarim Zare  Mohsen Shekouhy
Institution:
  • a Department of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr 75169, Iran
  • b Department of Chemistry, Payame Noor University (PNU), Bushehr 1698, Iran
  • Abstract:A new, convenient, and high yielding procedure for the synthesis of triazolo1,2-a]indazole-triones by the condensation reaction between dimedone, aryl aldehydes, and ueazoles in the presence of a catalytic amount of sulfonated polyethylene glycol (PEG-SO3H) as a highly stable and reusable eco-friendly degradable polymeric catalyst is described under solvent-free conditions. This procedure has also been applied successfully for the synthesis of novel spiro triazolo1,2-a]indazole-tetraones.
    Keywords:Combinatorial chemistry  Multi-component reaction  PEG-SO3H  Urazole  Triazolo[1  2-a]indazole-triones  Spiro triazolo[1  2-a]indazole-tetraone
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