|
|||||
|
|
A simple and convenient synthesis of 2-(perfluoroalkyl)-4H-chromenes from salicyl N-tosylimines or salicylaldehydes and methyl 2-perfluoroalkynoates |
|
| Authors: | Lei Lu Jiamei Wei Jie Chen Hongmei Deng Hui Zhang Weiguo Cao |
| Institution: | a Department of Chemistry, Shanghai University, Shanghai 200444, PR China b State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, PR China c Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, PR China d Instrumental Analysis and Research Center, Shanghai University, Shanghai 200444, PR China |
| Abstract: | Et3N-catalyzed reactions of salicyl N-tosylimines or salicylaldehydes with methyl 2-perfluoroalkynoates proceed smoothly at room temperature in dichloromethane (DCM) or dimethyl sulfoxide (DMSO) to give the corresponding fluorinated chromenes in good to excellent yields with high regioselectivity. |
| Keywords: | 2-(Perfluoroalkyl)-4H-chromene Salicyl N-tosylimine Salicylaldehyde Methyl 2-perfluoroalkynoate Regioselectivity |
| 本文献已被 ScienceDirect 等数据库收录！ | |