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Pd(II)-SPRIX catalyzed enantioselective construction of pyrrolizines/pyrroloindoles employing molecular oxygen as the sole oxidant
Authors:Chennan Ramalingan  Kazuhiro TakenakaHiroaki Sasai
Institution:The Institute of Scientific and Industrial Research (ISIR), Osaka University, Mihogaoka, Ibaraki, Osaka 567-0047, Japan
Abstract:Pd(II)-SPRIX catalyst coupled with an environmentally benign molecular oxygen as the sole oxidant successfully exploited the construction of pyrrolizines/pyrroloindoles, imperative scaffolds of bio-potent molecules through intramolecular C-N and C-C bond forming reactions in good yields with appreciable enantioselectivities.
Keywords:Palladium  Spiro bis(Isoxazoline)  Enantioselectivity  Molecular oxygen  Pyrrolizines  Pyrroloindoles
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