Synthesis of cholate-based pyridinium receptor and its recognition toward l-tryptophan |
| |
| Authors: | Dazhi Li Yunxu YangChao Yang Biwei HuBaolong Huo Lingwei XueAizhi Wang Feifei Yu |
| |
| Institution: | Department of Chemistry and Chemical Engineering, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China |
| |
| Abstract: | Four cholate-based pyridinium compounds were synthesized and their binding abilities toward unmodified amino acids were investigated by UV spectroscopy and fluorescence emission spectroscopy. Studies revealed that the recognition process involved hydrogen bonding, electrostatic force, and π–π interaction. The receptor 4a was found to recognize l-tryptophan specifically, and the complex was studied by 1H NMR spectroscopy. The receptors 4b and 4c showed very little recognition ability toward l-tryptophan, indicating the important role of the benzyl group at pyridinium ring. |
| |
| Keywords: | Molecular recognition Hydrogen bonding Conformation Host Amino acid |
| 本文献已被 ScienceDirect 等数据库收录！ |
