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Aptamers as molecular recognition elements for electrical nanobiosensors |
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| Authors: | Jeong-O Lee Hye-Mi So Eun-Kyoung Jeon Hyunju Chang Keehoon Won Yong Hwan Kim |
| Institution: | (1) Fusion-Biotechnology Research Center, Advanced Materials Division, Korea Research Institute of Chemical Technology, 100 Jang-dong, Yuseong-gu, Daejeon, 305–343, South Korea;(2) Department of Chemical and Biochemical Engineering, Dongguk University, 3–26 Pil-dong, Jung-gu, Seoul, 100–715, South Korea;(3) Department of Chemical Engineering, Kwangwoon University, 447–1 Wolgye-dong, Nowon-gu, Seoul, 139–701, South Korea |
| Abstract: | Recent advances in nanotechnology have enabled the development of nanoscale sensors that outperform conventional biosensors.
This review summarizes the nanoscale biosensors that use aptamers as molecular recognition elements. The advantages of aptamers
over antibodies as sensors are highlighted. These advantages are especially apparent with electrical sensors such as electrochemical
sensors or those using field-effect transistors.
Figure Feeling proteins with aptamer-functionalized carbon nanotubes |
| Keywords: | Aptamers Nanobiosensors Electrochemical aptamer sensors Field-effect transistor aptamer sensors |
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