Direct optical resolution of the enantiomers of novel chiral tetrahedral metal clusters by HPLC on a cellulose tris-(3,5-dimethylphenylcarbamate) stationary phase |
| |
Authors: | Wenzhi?Li Weiqiang?Zhang Quanyi?Zhao Email author" target="_blank">Yongmin?LiEmail author Chunlin?Ma Liren?Chen Yuanqi?Yin |
| |
Institution: | (1) Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Tianshui Road 342, 730000 Lanzhou, P.R. China;(2) Department of Chemistry, Liaocheng University, 252059 Liaocheng, P.R. China |
| |
Abstract: | The enantioseparation of seven novel chiral transition metal tetrahedral clusters has been achieved for the first time on cellulose derivatized with tris(3,5-dimethylphenylcarbamate) (CDMPC) as chiral stationary phase (CSP) and hexane containing different alcohols as modifiers as mobile phases. The effect of mobile-phase composition on enantioselectivity was studied, and the effect of structural variation of the solutes on their enantioseparation was also investigated. It was found that both the metal in the tetrahedral core and the ligand coordinated to the atom in the tetrahedral core had significant effects on the chromatographic behavior of the analytes. |
| |
Keywords: | Chiral stationary phase Cellulose tris(3 5-dimethylphenylcarbamate) Chiral transition-metal tetrahedral cluster Enantioseparation |
本文献已被 PubMed SpringerLink 等数据库收录! |