New approaches in layer by layer synthesis of collagen/hydroxyapatite composite materials |
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| Authors: | Andreia Ilie Ecaterina Andronescu Denisa Ficai Georgeta Voicu Maria Ficai Maria Maganu Anton Ficai |
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| Institution: | (1) Faculty of Applied Chemistry and Material Science, Politehnica University of Bucharest, 1-7 Polizu Street, 011061 Bucharest, Romania;(2) Center of Organic Chemistry “Costin D. Nenitescu”, Romanian Academy, 202B Splaiul Independentei, 050461 Bucharest, Romania; |
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| Abstract: | The aim of this work was to increase our understanding of collagen (COLL)/ hydroxyapatite (HA) composite materials; more specifically,
we focused on the study of the influence of the precursorconcentrations over the final content of deposited HA. We found that
the increase of the precursor concentrations led to better mineralization (on the basis of the content of deposited mineral
phase). Regardless of the precursor concentrations, the content of the deposited amount was found to increase with the increase
of the number of deposited layers. Quantification of the mineral phase amount was achieved by gravimetric determination. Based
on the determined deposition equation the number of layers can be easily determined in order to obtain composite materials
with desired content of mineral phase. |
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